Butterfield, D., Barone, E., Di Domenico, F., Cenini, G., Sultana, R., Murphy, M., … Head, E. (2012). Atorvastatin treatment in a dog preclinical model of Alzheimer’s disease leads to up-regulation of haem oxygenase-1 and is associated with reduced oxidative stress in brain. The International Journal of Neuropsychopharmacology, 15(7), 981-7. https://doi.org/10.1017/S1461145711001118

Di Domenico, F., Pupo, G., Tramutola, A., Giorgi, A., Schininà, M., Coccia, R., … Perluigi, M. (2014). Redox proteomics analysis of HNE-modified proteins in Down syndrome brain: clues for understanding the development of Alzheimer disease. Free Radical Biology & Medicine, 71, 270-280. https://doi.org/10.1016/j.freeradbiomed.2014.03.027

Perluigi, M., Pupo, G., Tramutola, A., Cini, C., Coccia, R., Barone, E., … Di Domenico, F. (2014). Neuropathological role of PI3K/Akt/mTOR axis in Down syndrome brain. Biochimica et Biophysica Acta, 1842(7), 1144-53. https://doi.org/10.1016/j.bbadis.2014.04.007

Cenini, G., Fiorini, A., Sultana, R., Perluigi, M., Cai, J., Klein, J., … Butterfield, D. (2014). An investigation of the molecular mechanisms engaged before and after the development of Alzheimer disease neuropathology in Down syndrome: a proteomics approach. Free Radical Biology & Medicine, 76, 89-95. https://doi.org/10.1016/j.freeradbiomed.2014.08.006

Butterfield, D., Di Domenico, F., Swomley, A., Head, E., & Perluigi, M. (2014). Redox proteomics analysis to decipher the neurobiology of Alzheimer-like neurodegeneration: overlaps in Down’s syndrome and Alzheimer’s disease brain. The Biochemical Journal, 463(2), 177-89. https://doi.org/10.1042/BJ20140772 (Original work published 2014)

Di Domenico, F., Pupo, G., Mancuso, C., Barone, E., Paolini, F., Arena, A., … Perluigi, M. Bach1 overexpression in Down syndrome correlates with the alteration of the HO-1/BVR-a system: insights for transition to Alzheimer’s disease. Journal of Alzheimer’s Disease : JAD, 44(4), 1107-20. https://doi.org/10.3233/JAD-141254 (Original work published 2015)

Triani, F., Tramutola, A., Di Domenico, F., Sharma, N., Butterfield, D., Head, E., … Barone, E. (2018). Biliverdin reductase-A impairment links brain insulin resistance with increased Aβ production in an animal model of aging: Implications for Alzheimer disease. Biochimica et Biophysica Acta. Molecular Basis of Disease, 1864(10), 3181-3194. https://doi.org/10.1016/j.bbadis.2018.07.005

Barone, E., Cenini, G., Di Domenico, F., Martin, S., Sultana, R., Mancuso, C., … Butterfield, D. (2011). Long-term high-dose atorvastatin decreases brain oxidative and nitrosative stress in a preclinical model of Alzheimer disease: a novel mechanism of action. Pharmacological Research, 63(3), 172-80. https://doi.org/10.1016/j.phrs.2010.12.007

Martin, S., Cenini, G., Barone, E., Dowling, A., Mancuso, C., Butterfield, D., … Head, E. (2011). Coenzyme Q10 and cognition in atorvastatin treated dogs. Neuroscience Letters, 501(2), 92-5. https://doi.org/10.1016/j.neulet.2011.06.054 (Original work published 2011)